hrp0084p1-10 | Adrenal | ESPE2015

Use of a Cord Blood Fluorescein Labeled Dexamethasone Monocyte Binding Assay to Study the Glucocorticoid Receptor in Neonates

Kashyap Arun , Aisenberg Javier , Ghanny Steven

Background: Glucocorticoids play an important role in the developing fetus, the most important of which is lung maturation by increasing surfactant production and release. Glucocorticoid receptor (GR) functioning changes throughout the fetal period, especially during the transition to extrauterine life. Given the importance of glucocorticoids in lung development and functioning, studying glucocorticoid sensitivity in this population would be helpful, especially in the preterm ...